Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 6/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 6/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 6/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360229 | 0.81 | DAO (0.54) | DAORAB9ALMNA | |
| SCHEMBL9656225 | 0.79 | DAO (0.55) | DAOSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL9360179 | 0.76 | MAOA (0.51) | DAOSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL11177471 | 0.75 | GRM5 (0.50) | DAOSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL29405082 | 0.75 | NPC1 (0.59) | DAOSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL432670 | 0.75 | NPC1 (0.59) | DAOSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL9364553 | 0.74 | ANPEP (0.43) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL9360622 | 0.73 | BRD4 (0.39) | DAOCYP1A2KDM4EMAPTLMNA | |
| SCHEMBL6639465 | 0.73 | NPC1 (0.50) | DAOSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL9360635 | 0.72 | BRD4 (0.38) | DAONPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |