Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.61 |
| ▸ | ACHE | P22303 | 7/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.59 |
| ▸ | THRA | P10827 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | PDE1A | P54750 | 4/20 | 0.53 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.53 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360046 | 0.95 | BCHE (0.58) | BCHEACHEEGFRTHRATHRB | |
| SCHEMBL7602314 | 0.91 | EGFR (0.63) | BCHEACHEEGFRTHRATHRB | |
| SCHEMBL9360115 | 0.87 | EGFR (0.63) | BCHEACHEEGFRTHRATHRB | |
| SCHEMBL9824528 | 0.86 | ALDH1A1 (0.57) | BCHEACHETHRATHRBKDM4E | |
| SCHEMBL7602709 | 0.85 | LTA4H (0.61) | BCHEACHEEGFRKDM4ELTA4H | |
| SCHEMBL9360203 | 0.85 | LSS (0.76) | BCHEACHELTA4H | |
| SCHEMBL9361471 | 0.83 | STS (0.54) | BCHEACHE | |
| SCHEMBL9360140 | 0.83 | LSS (0.70) | BCHEACHEKDM4ESMN1; SMN2PDE1A | |
| SCHEMBL9360056 | 0.83 | LSS (0.70) | BCHEACHEKDM4ESMN1; SMN2PDE1A | |
| SCHEMBL9360010 | 0.83 | LSS (0.70) | BCHEACHEKDM4ESMN1; SMN2PDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410359-B1 | Substituted aminoalkoxy-benzene-derivatives | HOFFMANN LA ROCHE (CH) | 1994-01-26 | — | — | EP | claimed |
| EP-0410359-A1 | Substituted aminoalkoxy-benzene-derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | claimed |
| EP-0410359-B1 | Substituted aminoalkoxy-benzene-derivatives | HOFFMANN LA ROCHE (CH) | 1994-01-26 | — | — | EP | disclosed |
| US-5214046-A | Synergistic mixtures, inhibitors of sterol biosynthesis | HOFFMANN-LA ROCHE INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5106878-A | Synergistic effects with other fungicides | HOFFMANN-LA ROCHE INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0410359-A1 | Substituted aminoalkoxy-benzene-derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | disclosed |