SCHEMBL9360313

SCHEMBL9360313

C=Cc1ccc(C2NC(C)(C)C(=O)O2)cc1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
SLC6A4 P31645 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A3 Q01959 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9359835 0.82 SLC6A4 (0.36) ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL9840519 0.78 ALDH1A1 (0.36) ALDH1A1LMNA
SCHEMBL9364698 0.76 SLC6A4 (0.32) SLC6A4SLC6A2SLC6A3
SCHEMBL9360926 0.74 ALDH1A1 (0.33) ALDH1A1
SCHEMBL9360043 0.68 ALDH1A1 (0.37) ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL12390507 0.66 ALDH1A1 (0.38) ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL1810452 0.65
SCHEMBL5959232 0.62 ALDH1A1 (0.38) ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL6112974 0.61
SCHEMBL4522016 0.61 SLC9A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463520-B1 2-(4-Alkenylphenyl)-5-oxazolones and polymers thereof POLAROID CORP (US) 1994-12-28 EP disclosed
EP-0463520-A1 2-(4-Alkenylphenyl)-5-oxazolones and polymers thereof POLAROID CORPORATION (US) 1992-01-02 EP disclosed
US-5039813-A 2-(4-alkenylphenyl)-5-oxazolones and polymers thereof POLAROID CORPORATION (US) 1991-08-13 US disclosed