Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360309 | 0.82 | DAO (0.35) | ERN1ALDH1A1GAADAOLMNA | |
| SCHEMBL9360622 | 0.81 | BRD4 (0.39) | BRD4ALDH1A1GAADAOMEN1 | |
| SCHEMBL9360323 | 0.72 | DAO (0.56) | ALDH1A1DAOLMNAKDM4ENPC1 | |
| SCHEMBL9364587 | 0.72 | ALDH1A1 (0.32) | ALDH1A1GAAEGFRERBB2KDM4E | |
| SCHEMBL9360293 | 0.68 | KMT2A (0.38) | ALDH1A1MEN1KMT2ALMNANPC1 | |
| SCHEMBL3296819 | 0.67 | KDM4E (0.42) | ERN1ALDH1A1GAANPSR1MEN1 | |
| SCHEMBL9360303 | 0.67 | IGFBP3 (0.36) | ALDH1A1GAADAOLMNASTAT3 | |
| SCHEMBL9360179 | 0.67 | MAOA (0.51) | ALDH1A1GAADAOKDM4ENPC1 | |
| SCHEMBL9360229 | 0.66 | DAO (0.54) | DAOLMNASTAT3EGFRIDO1 | |
| SCHEMBL9364553 | 0.66 | ANPEP (0.43) | ALDH1A1GAAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |