Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | AHCY | P23526 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826176 | 1.00 | ADORA3 (0.57) | ADORA3AHCYHIF1AYTHDC1SLC29A1 | |
| SCHEMBL21011280 | 0.88 | HIF1A (0.71) | ADORA3HIF1ASLC29A1 | |
| SCHEMBL548569 | 0.88 | HIF1A (0.71) | ADORA3HIF1ASLC29A1 | |
| SCHEMBL6267085 | 0.88 | HIF1A (0.71) | ADORA3HIF1ASLC29A1 | |
| SCHEMBL6267089 | 0.88 | HIF1A (0.71) | ADORA3HIF1ASLC29A1 | |
| SCHEMBL23982373 | 0.88 | HIF1A (0.71) | ADORA3HIF1ASLC29A1 | |
| SCHEMBL548570 | 0.88 | HIF1A (0.71) | ADORA3HIF1ASLC29A1 | |
| SCHEMBL8826179 | 0.87 | SLC29A1 (0.56) | ADORA3HIF1ASLC29A1 | |
| SCHEMBL8939236 | 0.87 | TSHR (0.59) | ADORA3HIF1ASLC29A1 | |
| SCHEMBL8826350 | 0.85 | SLC29A1 (0.51) | ADORA3HIF1ASLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625158-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |