Dehydrocostuslactone

Dehydrocostuslactone

SCHEMBL936050

C=C1C(=O)OC2C1CCC(=C)C1CCC(=C)C12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.46
PKM P14618 6/20 0.43
NLRP3 Q96P20 2/20 0.43
ALDH1A1 P00352 4/20 0.41
LMNA P02545 3/20 0.41
TP53 P04637 3/20 0.41
CYP3A4 P08684 3/20 0.41
NFKB1 P19838 2/20 0.41
CYP1A2 P05177 2/20 0.41
STAT6 P42226 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CASP1 P29466 1/20 0.41
PTGS2 P35354 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dehydrocostuslactone SCHEMBL31029489 1.00 CYP19A1 (0.46) CYP19A1PKMNLRP3ALDH1A1LMNA
Dehydrocostuslactone SCHEMBL699070 1.00 CYP19A1 (0.46) CYP19A1PKMNLRP3ALDH1A1LMNA
Dehydrozaluzanin C SCHEMBL17214360 0.83 CYP19A1 (0.42) CYP19A1PKMNLRP3ALDH1A1LMNA
Isozaluzanin C SCHEMBL24453721 0.80 PKM (0.40) CYP19A1PKMNLRP3ALDH1A1LMNA
Isozaluzanin C SCHEMBL17214374 0.80 PKM (0.40) CYP19A1PKMNLRP3ALDH1A1LMNA
Eremanthin SCHEMBL9516039 0.79 CYP19A1 (0.56) CYP19A1PKMNLRP3ALDH1A1LMNA
SCHEMBL22305504 0.73 PTGS2 (0.40) CYP19A1PKMNLRP3CYP3A4PTGS2
SCHEMBL22305507 0.72 PKM (0.41) CYP19A1PKMNLRP3ALDH1A1LMNA
SCHEMBL17147746 0.71 PKM (0.55) CYP19A1PKMNLRP3ALDH1A1LMNA
SCHEMBL17147754 0.71 PKM (0.55) CYP19A1PKMNLRP3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025025254-A1 PATCHOULI QI-RECTIFYING TABLET AND PREPARATION PROCESS THEREFOR, AND QUANTITATIVE AND QUALITATIVE DETERMINATION METHOD FOR MULTIPLE COMPONENTS IN PATCHOULI QI-RECTIFYING TABLET 上海和黄药业有限公司 2025-02-06 WO disclosed
CN-108627588-B Detection method of Zhengqi tablet fingerprint and application thereof 上海和黄药业有限公司 2024-03-12 CN disclosed
CN-116983381-A Positive qi tablet and preparation process thereof and multi-component quantitative and qualitative determination method thereof 上海和黄药业有限公司 2023-11-03 CN disclosed
CN-112748211-A Detection method of gas-phase fingerprint spectrum of vital qi tablet and application thereof 上海和黄药业有限公司 2021-05-04 CN disclosed
CN-108627588-A A kind of detection method of healthy tendency piece finger-print and its application 上海和黄药业有限公司 2018-10-09 CN disclosed
WO-2011010496-A1 MELANIN PRODUCTION INHIBITOR 株式会社ファンケル (JP) 2011-01-27 WO disclosed