SCHEMBL936053

SCHEMBL936053

CCCCCCC(CCCC)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 1/20 0.54
SELL P14151 9/20 0.50
SELP P16109 9/20 0.50
SELE P16581 5/20 0.50
FOLH1 Q04609 2/20 0.50
RIMKLA Q8IXN7 1/20 0.50
NAALAD2 Q9Y3Q0 1/20 0.50
PLA2G2C Q5R387 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9981032 0.98 NOD1 (0.55) NOD1SELLSELPSELEFOLH1
SCHEMBL619960 0.89 CA2 (0.53) NOD1FOLH1RIMKLANAALAD2PLA2G2C
SCHEMBL6413427 0.89 CA2 (0.53) NOD1FOLH1RIMKLANAALAD2PLA2G2C
SCHEMBL6413425 0.89 CA2 (0.53) NOD1FOLH1RIMKLANAALAD2PLA2G2C
SCHEMBL1636628 0.89 CA2 (0.53) NOD1FOLH1RIMKLANAALAD2PLA2G2C
SCHEMBL19326364 0.85 FOLH1 (0.58) FOLH1RIMKLANAALAD2
SCHEMBL19695690 0.85 NOD1 (0.54) NOD1FOLH1RIMKLANAALAD2PLA2G2C
SCHEMBL15846449 0.85 NOD1 (0.54) NOD1FOLH1RIMKLANAALAD2PLA2G2C
SCHEMBL15847221 0.85 NOD1 (0.54) NOD1FOLH1RIMKLANAALAD2PLA2G2C
SCHEMBL15846812 0.85 NOD1 (0.54) NOD1FOLH1RIMKLANAALAD2PLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2525809-B1 GLUCAGON-GLP1 DUAL AGONISTS FOR USE IN THE TREATMENT OF CARDIAC CONDITIONS ZEALAND PHARMA AS (DK) 2016-08-03 EP claimed
US-20160120951-A1 ACYLATED GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2016-05-05 US claimed
US-20160000883-A1 COMBINATION OF ACYLATED GLUCAGON ANALOGUES WITH INSULIN ANALOGUES ZEALAND PHARMA A/S (DK) 2016-01-07 US claimed
EP-2454282-B1 ACYLATED GLUCAGON ANALOGUES ZEALAND PHARMA AS (DK) 2015-03-04 EP claimed
US-20140011733-A1 COMBINATION OF ACYLATED GLUCAGON ANALOGUES WITH INSULIN ANALOGUES ZEALAND PHARMA A/S (DK) 2014-01-09 US claimed
US-20130157953-A1 TREATMENT OF CARDIAC CONDITIONS ZEALAND PHARMA A/S (DK) 2013-06-20 US claimed
US-20120178670-A1 ACYLATED GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2012-07-12 US claimed
EP-2585482-B1 GLUCAGON ANALOGUES ZEALAND PHARMA AS (DK) 2019-03-27 EP disclosed
US-20190076506-A1 ACYLATED GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2019-03-14 US disclosed
US-10004786-B2 Acylated glucagon analogues ZEALAND PHARMA A/S (DK) 2018-06-26 US disclosed
EP-2525809-B1 GLUCAGON-GLP1 DUAL AGONISTS FOR USE IN THE TREATMENT OF CARDIAC CONDITIONS ZEALAND PHARMA AS (DK) 2016-08-03 EP disclosed
US-20160120951-A1 ACYLATED GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2016-05-05 US disclosed
US-20160000883-A1 COMBINATION OF ACYLATED GLUCAGON ANALOGUES WITH INSULIN ANALOGUES ZEALAND PHARMA A/S (DK) 2016-01-07 US disclosed
EP-2454282-B1 ACYLATED GLUCAGON ANALOGUES ZEALAND PHARMA AS (DK) 2015-03-04 EP disclosed
US-20140011733-A1 COMBINATION OF ACYLATED GLUCAGON ANALOGUES WITH INSULIN ANALOGUES ZEALAND PHARMA A/S (DK) 2014-01-09 US disclosed
US-20130157953-A1 TREATMENT OF CARDIAC CONDITIONS ZEALAND PHARMA A/S (DK) 2013-06-20 US disclosed
US-20130157929-A1 GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2013-06-20 US disclosed
US-20120178670-A1 ACYLATED GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2012-07-12 US disclosed
EP-2454282-A1 ACYLATED GLUCAGON ANALOGUES Zealand Pharma A/S (DK) 2012-05-23 EP disclosed
WO-2011006497-A1 ACYLATED GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2011-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160120951-A1 ACYLATED GLUCAGON ANALOGUES GLP1R, GCGR, GIPR NOD1 1032/4885SELL 1618/4885SELP 2803/4885
US-10004786-B2 Acylated glucagon analogues GLP1R, GCGR, GIPR NOD1 1016/4885SELL 1695/4885SELP 2869/4885
US-20140011733-A1 COMBINATION OF ACYLATED GLUCAGON ANALOGUES WITH INSULIN ANALOGUES IAPP, GLP1R, GCG NOD1 1995/4885SELL 1520/4885SELP 4336/4885
US-20190076506-A1 ACYLATED GLUCAGON ANALOGUES GLP1R, GCGR, GIPR NOD1 1032/4885SELL 1618/4885SELP 2803/4885
US-20160000883-A1 COMBINATION OF ACYLATED GLUCAGON ANALOGUES WITH INSULIN ANALOGUES IAPP, GLP1R, GCG NOD1 1995/4885SELL 1520/4885SELP 4336/4885
US-20120178670-A1 ACYLATED GLUCAGON ANALOGUES GLP1R, GCGR, GIPR NOD1 1032/4885SELL 1618/4885SELP 2803/4885
US-20130157953-A1 TREATMENT OF CARDIAC CONDITIONS GLP1R, GCGR, TNNT2 NOD1 1889/4885SELL 1395/4885SELP 2204/4885
US-20130157929-A1 GLUCAGON ANALOGUES GLP1R, GCGR, GIPR NOD1 429/4885SELL 1271/4885SELP 2837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.