Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560081 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TDP1CYP3A4ALOX15USP2 | |
| SCHEMBL9356495 | 0.82 | BID (0.49) | ALOX5CYSLTR2CYSLTR1LMNA | |
| SCHEMBL9356843 | 0.82 | BID (0.49) | ALOX5CYSLTR2CYSLTR1LMNA | |
| SCHEMBL9356869 | 0.82 | CYSLTR2 (0.53) | ALOX15CYSLTR2CYSLTR1HSD17B10 | |
| SCHEMBL9356850 | 0.82 | BID (0.49) | ALOX5CYSLTR2CYSLTR1LMNA | |
| SCHEMBL9356490 | 0.82 | BID (0.49) | ALOX5CYSLTR2CYSLTR1LMNA | |
| SCHEMBL10445309 | 0.82 | BID (0.49) | ALOX5CYSLTR2CYSLTR1LMNA | |
| SCHEMBL9356497 | 0.79 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1 | |
| SCHEMBL9360678 | 0.78 | KMT2A (0.43) | ALDH1A1TDP1CYP3A4ALOX15USP2 | |
| SCHEMBL9360672 | 0.78 | KMT2A (0.43) | ALDH1A1TDP1CYP3A4ALOX15USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403250-B1 | Phenylglycidamides useful for preparing alpha-hydroxy-beta-sulfido-arylpropionic acid derivatives | SMITHKLINE BEECHAM CORP (US) | 1994-11-23 | — | — | EP | disclosed |
| EP-0403250-A2 | Phenylglycidamides useful for preparing alpha-hydroxy-beta-sulfido-arylpropionic acid derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |