Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | CES1 | P23141 | 3/20 | 0.31 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360569 | 0.86 | HDAC1 (0.45) | CYSLTR2CYSLTR1HDAC1HDAC8SIRT2 | |
| SCHEMBL9356869 | 0.83 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9356843 | 0.83 | BID (0.49) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9356495 | 0.83 | BID (0.49) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL10445309 | 0.83 | BID (0.49) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9356850 | 0.83 | BID (0.49) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9356490 | 0.83 | BID (0.49) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9360562 | 0.80 | HDAC1 (0.46) | CYSLTR2CYSLTR1ATMHDAC1HDAC8 | |
| SCHEMBL9356518 | 0.79 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1MCL1TBXA2R | |
| SCHEMBL9360639 | 0.79 | ALDH1A1 (0.40) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403250-B1 | Phenylglycidamides useful for preparing alpha-hydroxy-beta-sulfido-arylpropionic acid derivatives | SMITHKLINE BEECHAM CORP (US) | 1994-11-23 | — | — | EP | disclosed |
| EP-0403250-A2 | Phenylglycidamides useful for preparing alpha-hydroxy-beta-sulfido-arylpropionic acid derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |