SCHEMBL936066

SCHEMBL936066

CCCCCCCCCCCCCCCCCCCCCC(=O)OC1=C(O)C(=O)O[C@@H]1[C@@H](O)CO

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.60
HSPD1 P10809 1/20 0.60
HSPE1 P61604 1/20 0.60
TST Q16762 1/20 0.60
RECQL P46063 1/20 0.60
BLM P54132 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
TYR P14679 1/20 0.50
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PRKCA P17252 9/20 0.43
KDM4E B2RXH2 1/20 0.42
DUSP3 P51452 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL874725 1.00 MAPT (0.60) MAPTHSPD1HSPE1TSTRECQL
SCHEMBL15364 1.00 MAPT (0.60) MAPTHSPD1HSPE1TSTRECQL
SCHEMBL16950234 1.00 MAPT (0.60) MAPTHSPD1HSPE1TSTRECQL
SCHEMBL875292 1.00 MAPT (0.60) MAPTHSPD1HSPE1TSTRECQL
SCHEMBL444603 1.00 MAPT (0.60) MAPTHSPD1HSPE1TSTRECQL
SCHEMBL1503121 1.00 MAPT (0.60) MAPTHSPD1HSPE1TSTRECQL
SCHEMBL16201 1.00 MAPT (0.60) MAPTHSPD1HSPE1TSTRECQL
SCHEMBL875399 1.00 MAPT (0.60) MAPTHSPD1HSPE1TSTRECQL
SCHEMBL22730055 1.00 MAPT (0.60) MAPTHSPD1HSPE1TSTRECQL
SCHEMBL875356 1.00 MAPT (0.60) MAPTHSPD1HSPE1TSTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3506907-B1 COMBINATION CANCER THERAPY WITH A PENTAAZA MACROCYCLIC RING COMPLEX AND AN ASCORBATE COMPOUND GALERA LABS LLC (US) 2023-06-07 EP claimed
US-20230165929-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS RENOVION, INC. 2023-06-01 US claimed
US-20220304977-A1 COMBINATION CANCER THERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX AND ASCORBATE COMPOUND BIOSSIL INC. (CA) 2022-09-29 US claimed
US-11219614-B2 Combination cancer therapy with pentaaza macrocyclic ring complex and ascorbate compound GALERA LABS, LLC (US) 2022-01-11 US claimed
US-20190351005-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS RENOVION, INC. 2019-11-21 US claimed
EP-3541401-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH GLUTATHIONE COMPOSITIONS Renovion, Inc. (US) 2019-09-25 EP claimed
US-20190209524-A1 COMBINATION CANCER THERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX AND ASCORBATE COMPOUND BIOSSIL INC. (CA) 2019-07-11 US claimed
EP-3506907-A2 COMBINATION CANCER THERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX AND ASCORBATE COMPOUND Galera Labs, LLC (US) 2019-07-10 EP claimed
WO-2018094278-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH GLUTATHIONE COMPOSITIONS RENOVION, INC. (US) 2018-05-24 WO claimed
US-9649283-B2 Treatment of urinary incontinence using nitrone spin traps PERRICONE NICHOLAS V (US) 2017-05-16 US claimed
WO-2009046033-A2 SILICONE GEL-BASED COMPOSITIONS FOR WOUND HEALING AND SCAR REDUCTION VALEANT PHARMACEUTICALS INTERNATIONAL (US) 2009-04-09 WO claimed
EP-0944310-B8 STABILIZED ASCORBYL COMPOSITIONS PERRICONE NICHOLAS V DR (US) 2005-06-01 EP claimed
EP-0944310-B1 STABILIZED ASCORBYL COMPOSITIONS PERRICONE NICHOLAS V DR (US) 2005-04-06 EP claimed
WO-2001082878-A1 TREATMENT OF SKIN DAMAGE USING ACETYL CARNITINE AND PHOSPHATIDYLCHOLINE AND/OR ASCORBYL FATTY ACID ESTERS PERRICONE NICHOLAS V (US) 2001-11-08 WO claimed
WO-2001082861-A2 TREATMENT OF SKIN DAMAGE USING CONJUGATED LINOLEIC ACID AND ASCORBYL FATTY ACID ESTERS PERRICONE NICHOLAS V (US) 2001-11-08 WO claimed
US-6296861-B1 Treatment of skin damage using conjugated linoleic acid and ascorbyl fatty acid esters THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT 2001-10-02 US claimed
EP-0944310-A4 STABILIZED ASCORBYL COMPOSITIONS PERRICONE NICHOLAS V DR (US) 2001-01-10 EP claimed
US-6162419-A Stabilized ascorbyl compositions Perricone, Nicholas V. (US) 2000-12-19 US claimed
EP-0944310-A1 STABILIZED ASCORBYL COMPOSITIONS PERRICONE, Nicholas V., Dr. (US) 1999-09-29 EP claimed
WO-1998023152-A1 STABILIZED ASCORBYL COMPOSITIONS PERRICONE NICHOLAS V (US) 1998-06-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220304977-A1 COMBINATION CANCER THERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX AND ASCORBATE COMPOUND FOLR1, SLC19A1, FOLR2 MAPT 3683/4885HSPD1 1336/4885HSPE1 905/4885
US-20230165929-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS GPX1, GPX4, GSR MAPT 2926/4885HSPD1 456/4885HSPE1 318/4885
US-11219614-B2 Combination cancer therapy with pentaaza macrocyclic ring complex and ascorbate compound FOLR1, SLC19A1, FOLR2 MAPT 3683/4885HSPD1 1336/4885HSPE1 905/4885
US-20190351005-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS GPX1, GPX4, GSR MAPT 2926/4885HSPD1 456/4885HSPE1 318/4885
US-20190209524-A1 COMBINATION CANCER THERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX AND ASCORBATE COMPOUND FOLR1, SLC19A1, FOLR2 MAPT 3683/4885HSPD1 1336/4885HSPE1 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.