Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.49 |
| ▸ | DRD3 | P35462 | 10/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360297 | 0.77 | ACHE (0.53) | DRD2DRD3DRD4HTR2AHTR7 | |
| SCHEMBL9360735 | 0.77 | DRD2 (0.45) | DRD2DRD3DRD4HTR2AHTR7 | |
| SCHEMBL9360715 | 0.70 | MAPT (0.56) | CA1CA2 | |
| SCHEMBL21663684 | 0.69 | DRD2 (0.56) | DRD2DRD3DRD4HTR2AHTR7 | |
| SCHEMBL22252849 | 0.68 | ACHE (0.78) | DRD2DRD3DRD4HTR2AHTR7 | |
| SCHEMBL7395278 | 0.66 | ACHE (0.69) | DRD2DRD3DRD4HTR2AHTR7 | |
| SCHEMBL7102137 | 0.66 | ADRA1A (0.48) | DRD2DRD3DRD4HTR2AHTR7 | |
| SCHEMBL7100693 | 0.66 | ADRA1A (0.48) | DRD2DRD3DRD4HTR2AHTR7 | |
| SCHEMBL16227246 | 0.65 | ACHE (0.68) | DRD2DRD3DRD4HTR2AHTR7 | |
| SCHEMBL9249869 | 0.65 | ACHE (0.68) | DRD2DRD3DRD4HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |