SCHEMBL9360908

SCHEMBL9360908

C=C(C)c1ccc(C2=NC(C)(C)C(=O)O2)cc1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CLK1 P49759 1/20 0.31
CLK2 P49760 1/20 0.31
DYRK1A Q13627 1/20 0.31
HIPK1 Q86Z02 1/20 0.31
HIPK2 Q9H2X6 1/20 0.31
HIPK3 Q9H422 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
ALDH1A1 P00352 2/20 0.30
HPGD P15428 2/20 0.30
XDH P47989 1/20 0.30
MAPT P10636 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24241764 0.77 MAPT (0.44) ALDH1A1HPGDMAPT
SCHEMBL24241601 0.77 ALDH1A1 (0.36) ALDH1A1HPGDMAPTKDM4E
SCHEMBL6468303 0.76 ALDH1A1 (0.35) ALDH1A1HPGDMAPT
Hydrochloric Acid SCHEMBL11729437 0.75 ALDH1A1 (0.45) ALDH1A1HPGDMAPTKDM4E
SCHEMBL22505234 0.74 KDM4E (0.44) ALDH1A1XDHMAPTKDM4E
SCHEMBL6698057 0.71 ALDH1A1 (0.36) ALDH1A1HPGDMAPTKDM4E
SCHEMBL24534547 0.69 ALDH1A1 (0.47) ALDH1A1HPGDMAPTKDM4E
SCHEMBL508723 0.69
SCHEMBL10583841 0.67 ALOX15 (0.39) ALDH1A1HPGDMAPTKDM4E
SCHEMBL9516265 0.66 MAPT (0.44) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463520-B1 2-(4-Alkenylphenyl)-5-oxazolones and polymers thereof POLAROID CORP (US) 1994-12-28 EP disclosed
EP-0463520-A1 2-(4-Alkenylphenyl)-5-oxazolones and polymers thereof POLAROID CORPORATION (US) 1992-01-02 EP disclosed
US-5039813-A 2-(4-alkenylphenyl)-5-oxazolones and polymers thereof POLAROID CORPORATION (US) 1991-08-13 US disclosed