SCHEMBL6698057

SCHEMBL6698057

CC1(C)N=C(c2cccc(C3=NC(C)(C)C(=O)O3)c2)OC1=O

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
MAPT P10636 4/20 0.36
HPGD P15428 3/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NPC1 O15118 3/20 0.33
RAB9A P51151 2/20 0.33
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.31
DAPK3 O43293 1/20 0.31
PSMB8 P28062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3384398 0.87 ALDH1A1 (0.46) ALDH1A1MAPTHPGDMEN1KMT2A
Hydrochloric Acid SCHEMBL11729437 0.85 ALDH1A1 (0.45) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL24241764 0.84 MAPT (0.44) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL24534547 0.82 ALDH1A1 (0.47) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL10583841 0.77 ALOX15 (0.39) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL2317085 0.76 ALDH1A1 (0.36) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL24241601 0.76 ALDH1A1 (0.36) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL6702374 0.76 ALOX15 (0.38) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL22505234 0.74 KDM4E (0.44) ALDH1A1MAPTNPC1RAB9AKDM4E
SCHEMBL6468303 0.73 ALDH1A1 (0.35) ALDH1A1MAPTHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0019061-B1 PROCESS FOR PRODUCING AROMATIC POLYESTERS HAVING INCREASED DEGREES OF POLYMERIZATION AND MOULDED ARTICLES COMPOSED OF THESE POLYESTERS TEIJIN LIMITED (JP) 1984-08-08 EP claimed
US-4291152-A CHAIN EXTENSION WITH BICYCLIC OXAZINONE OR OXAZOLONE TEIJIN LIMITED (JP) 1981-09-22 US claimed
EP-0019061-A1 Process for producing aromatic polyesters having increased degrees of polymerization and moulded articles composed of these polyesters TEIJIN LIMITED (JP) 1980-11-26 EP claimed
US-20040068059-A1 Aliphatic polyester copolymer and process for producing the same, biodegradable resin molding based on aliphatic polyester, and lactone-containing resin DAICEL CHEMICAL INDUSTRIES LTD. (JP) 2004-04-08 US disclosed
EP-1354908-A1 ALIPHATIC POLYESTER COPOLYMER AND PROCESS FOR PRODUCING THE SAME, BIODEGRADABLE RESIN MOLDING BASED ON ALIPHATIC POLYESTER, AND LACTONE-CONTAINING RESIN DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2003-10-22 EP disclosed
EP-0710684-B1 Preparation process of polyhydroxycarboxylic acid MITSUI CHEMICALS INC (JP) 2001-01-31 EP disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed
US-5139885-A Aroamtic polester, halogenated diol, diglycidyl or dicarboxylic acid and a-di-heterocyclic compound; flexible heat stable POLYPLASTICS CO., LTD. (JP) 1992-08-18 US disclosed
US-5079284-A Halogenated nitrogen heterocycle as flame retardant POLYPLASTICS CO., LTD. (JP) 1992-01-07 US disclosed
US-4954541-A POLYESTER, HALOGENATED COMPOUND, HETEROCYCLIC COMPOUND POLYPLASTICS CO., LTD. (JP) 1990-09-04 US disclosed
US-4898923-A FROM DIAMINES AND DIPYRYLIUM COPOLYMERIZED WITH DIISOCYANATES, DIACIDS AND DIAZLACTONES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-02-06 US disclosed
US-4841021-A AS REDOX POLYMERS, POLYELECTROLYTES, ELECTROCHROMIC MATERIALS OR ION EXCHANGERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-06-20 US disclosed
EP-0019061-B1 PROCESS FOR PRODUCING AROMATIC POLYESTERS HAVING INCREASED DEGREES OF POLYMERIZATION AND MOULDED ARTICLES COMPOSED OF THESE POLYESTERS TEIJIN LIMITED (JP) 1984-08-08 EP disclosed
EP-0020944-B1 PROCESS FOR PRODUCING AROMATIC POLYESTERS HAVING AN INCREASED DEGREE OF POLYMERISATION, THESE AROMATIC POLYESTERS, PROCESS FOR PRODUCING MOLDED ARTICLES COMPOSED THEREOF, AND THESE MOLDED ARTICLES TEIJIN LIMITED (JP) 1983-07-27 EP disclosed
US-4331800-A CHAIN EXTENSION WITH A BIS/CYCLIC IMINOETHER TEIJIN LIMITED (JP) 1982-05-25 US disclosed
US-4291152-A CHAIN EXTENSION WITH BICYCLIC OXAZINONE OR OXAZOLONE TEIJIN LIMITED (JP) 1981-09-22 US disclosed
EP-0020944-A1 Process for producing aromatic polyesters having an increased degree of polymerisation, these aromatic polyesters, process for producing molded articles composed thereof, and these molded articles TEIJIN LIMITED (JP) 1981-01-07 EP disclosed
EP-0019061-A1 Process for producing aromatic polyesters having increased degrees of polymerization and moulded articles composed of these polyesters TEIJIN LIMITED (JP) 1980-11-26 EP disclosed