Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512850 | 0.82 | ALDH1A1 (0.33) | TSHRHTR2CKDM1A | |
| SCHEMBL11371142 | 0.78 | KDM4E (0.34) | TSHR | |
| SCHEMBL11599949 | 0.76 | HTR2C (0.33) | TSHRHTR2CKDM1A | |
| SCHEMBL6854408 | 0.74 | ALDH1A1 (0.38) | TSHR | |
| SCHEMBL9876114 | 0.72 | SLC6A4 (0.38) | KDM1A | |
| SCHEMBL9876112 | 0.72 | SLC6A4 (0.38) | KDM1A | |
| SCHEMBL22546490 | 0.66 | HTR2C (0.33) | HTR2CKDM1A | |
| SCHEMBL13988672 | 0.66 | TSHR (0.46) | TSHRHTR2CKDM1A | |
| SCHEMBL21937589 | 0.64 | FFAR4 (0.43) | TSHRHTR2CKDM1A | |
| SCHEMBL20009112 | 0.60 | FFAR4 (0.56) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289924-B1 | Process for the preparation of pyridines | HOELDERICH WOLFGANG PROF DR (DE) | 1994-12-21 | — | — | EP | disclosed |
| US-5081247-A | Reacting a 2-alkoxy-2,3-dihydro-4H-pyran or a glutaraldehyde with ammonia in the presence of a zeolite | BASF AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | disclosed |
| EP-0289924-A2 | Process for the preparation of pyridines | DEGUSSA AG (DE) | 1988-11-09 | — | — | EP | disclosed |