Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PLK1 | P53350 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366141 | 0.86 | SMN1; SMN2 (0.57) | ACAT1MAPTMEN1POLBKMT2A | |
| SCHEMBL9502479 | 0.83 | ACAT1 (0.80) | ACAT1TP53PLK1 | |
| SCHEMBL9361393 | 0.82 | MAPT (0.53) | ACAT1MAPTMEN1POLBKMT2A | |
| SCHEMBL9361027 | 0.82 | ACAT1 (1.00) | ACAT1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9361036 | 0.82 | ACAT1 (1.00) | ACAT1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9361187 | 0.82 | ACAT1 (1.00) | ACAT1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6940849 | 0.82 | ACAT1 (1.00) | ACAT1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9365235 | 0.82 | ACAT1 (1.00) | ACAT1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9365137 | 0.82 | ACAT1 (1.00) | ACAT1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9502352 | 0.81 | ACAT1 (0.77) | ACAT1MAPTKMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424194-B1 | Benzanilide derivatives and their use as anti-atherosclerotic agents | RHONE POULENC SANTE (FR) | 1994-08-31 | — | — | EP | disclosed |
| US-5159114-A | Anticholesterol agents | RHONE-POULENC SANTE (FR) | 1992-10-27 | — | — | US | disclosed |
| EP-0424194-A2 | Benzanilide derivatives and their use as anti-atherosclerotic agents | RHONE-POULENC SANTE (FR) | 1991-04-24 | — | — | EP | disclosed |