Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357724 | 0.80 | LMNA (0.52) | ALDH3A1ALDH1A1AURKBHTTNPSR1 | |
| SCHEMBL11443217 | 0.79 | ALDH1A1 (0.42) | ALDH1A1AURKBHTTNPSR1GAA | |
| SCHEMBL16986012 | 0.77 | HTT (0.48) | ALDH1A1HTTNPSR1GAAHSD17B10 | |
| SCHEMBL10805152 | 0.74 | HSD17B10 (0.54) | ALDH1A1AURKBHTTNPSR1HSD17B10 | |
| SCHEMBL7215753 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HTTMAPTHPGDSMN1; SMN2 | |
| SCHEMBL7684154 | 0.74 | KDM4E (0.54) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL31299763 | 0.74 | ALDH1A3 (0.65) | ALDH1A3ALDH3A1ALDH1A1KDM4EHPGD | |
| SCHEMBL29957610 | 0.74 | KDM4E (0.54) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL29950977 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HTTMAPTHPGDSMN1; SMN2 | |
| SCHEMBL11695579 | 0.73 | ALDH1A1 (0.52) | ALDH1A3ALDH3A1ALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326133-B1 | Organic nonlinear optical material and nonlinear optical device | NIPPON TELEGRAPH & TELEPHONE (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4999139-A | Aminonitrostyrene Compound; Including a Polarizer, an Optical Resonator an a Reflector | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1991-03-12 | — | — | US | disclosed |
| US-4997595-A | Organic nonlinear optical material and nonlinear optical device | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0326133-A2 | Organic nonlinear optical material and nonlinear optical device | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1989-08-02 | — | — | EP | disclosed |