Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.48 |
| ▸ | RNF4 | P78317 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364120 | 0.82 | CES1 (0.46) | EPHX2TSHR | |
| SCHEMBL9362574 | 0.79 | LMNA (0.53) | FFAR1TSHR | |
| SCHEMBL1594428 | 0.79 | SRD5A2 (0.58) | LTA4HSRD5A2EPHX2RNF4FFAR1 | |
| SCHEMBL8694782 | 0.75 | SRD5A2 (0.58) | LTA4HSRD5A2EPHX2FFAR1NR3C1 | |
| SCHEMBL510124 | 0.74 | LTA4H (0.61) | LTA4HSRD5A2RNF4FFAR1NR1H2 | |
| SCHEMBL5563462 | 0.74 | SRD5A2 (0.62) | LTA4HSRD5A2EPHX2RNF4FFAR1 | |
| SCHEMBL28267455 | 0.74 | LTA4H (0.52) | LTA4HSRD5A2EPHX2FFAR1NR3C1 | |
| SCHEMBL9252738 | 0.73 | LTA4H (0.61) | LTA4HSRD5A2EPHX2FFAR1NR3C1 | |
| SCHEMBL9711192 | 0.73 | LTA4H (0.61) | LTA4HSRD5A2EPHX2FFAR1NR3C1 | |
| SCHEMBL1145770 | 0.73 | SRD5A2 (0.83) | LTA4HSRD5A2FFAR1NR3C1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462148-B1 | SUBSTITUTED 2-PROPENYL DERIVATIVES OF NITROGEN HETEROCYCLES | UNIROYAL CHEM CO INC (US) | 1994-06-01 | — | — | EP | disclosed |
| EP-0462148-A1 | SUBSTITUTED 2-PROPENYL DERIVATIVES OF NITROGEN HETEROCYCLES. | UNIROYAL CHEM CO INC (US) | 1991-12-27 | — | — | EP | disclosed |
| WO-1990010627-A1 | SUBSTITUTED 2-PROPENYL DERIVATIVES OF NITROGEN HETEROCYCLES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1990-09-20 | — | — | WO | disclosed |
| US-4950671-A | FUNGICIDES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1990-08-21 | — | — | US | disclosed |