Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 3/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362150 | 0.94 | CCKBR (0.37) | GRIN2BPTGDR2ACHEMTNR1AMTNR1B | |
| SCHEMBL9362327 | 0.94 | CCKBR (0.37) | GRIN2BPTGDR2ACHEMTNR1AMTNR1B | |
| SCHEMBL9363059 | 0.92 | GRIN2B (0.35) | GRIN2BPTGDR2ACHEHSD17B1HSD17B2 | |
| SCHEMBL9362630 | 0.89 | CCKBR (0.40) | GRIN2BPTGDR2CCKBRMAPTALDH1A1 | |
| SCHEMBL8919334 | 0.89 | CCKBR (0.40) | GRIN2BPTGDR2CCKBRMAPTALDH1A1 | |
| SCHEMBL9363000 | 0.89 | CCKBR (0.33) | HSD17B2CCKBRMAPTALDH1A1 | |
| SCHEMBL9362676 | 0.89 | CCKBR (0.33) | HSD17B2CCKBRLMNAMAPTALDH1A1 | |
| SCHEMBL9362251 | 0.87 | CCKBR (0.42) | GRIN2BPTGDR2CCKBRMAPTALDH1A1 | |
| SCHEMBL9365784 | 0.86 | SIGMAR1 (0.35) | OPRM1CCKBR | |
| SCHEMBL9361986 | 0.86 | CCKBR (0.37) | GRIN2BCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625145-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1994-11-23 | — | — | EP | disclosed |