Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362676 | 0.91 | CCKBR (0.33) | CCKBRHSD17B2ALDH1A1MAPTPKM | |
| SCHEMBL8919334 | 0.91 | CCKBR (0.40) | CCKBRALDH1A1MAPTPKM | |
| SCHEMBL9362630 | 0.91 | CCKBR (0.40) | CCKBRALDH1A1MAPTPKM | |
| SCHEMBL9362251 | 0.90 | CCKBR (0.42) | CCKBRALDH1A1MAPTPKM | |
| SCHEMBL9365784 | 0.89 | SIGMAR1 (0.35) | CCKBROPRD1 | |
| SCHEMBL9361986 | 0.89 | CCKBR (0.37) | CCKBR | |
| SCHEMBL9362255 | 0.89 | GRIN2B (0.37) | CCKBRHSD17B2ALDH1A1MAPT | |
| SCHEMBL9367185 | 0.87 | CCKBR (0.44) | CCKBRALDH1A1MAPTPKM | |
| SCHEMBL9363055 | 0.87 | CCKBR (0.33) | CCKBR | |
| SCHEMBL9365828 | 0.86 | CCKBR (0.37) | CCKBROPRD1ALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625145-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993015059-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1993-08-05 | — | — | WO | disclosed |