Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9690943 | 0.98 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL2011683 | 0.76 | — | — | |
| SCHEMBL2011682 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2239390 | 0.75 | EGLN1 (0.57) | CYP2D6LMNABLMALOX15TSHR | |
| Hydrochloric Acid SCHEMBL2239385 | 0.75 | EGLN1 (0.57) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL5765192 | 0.73 | EGLN1 (0.45) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL6745739 | 0.72 | ALOX15 (1.00) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL179769 | 0.72 | ALOX15 (1.00) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL1321720 | 0.72 | ALOX15 (1.00) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL179767 | 0.72 | ALOX15 (1.00) | CYP2D6LMNABLMALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418143-B1 | Dicarboxylic acids derivatives containing a nitrogen or oxygen heteroring, process for their preparation and their use as medicines | ROUSSEL UCLAF (FR) | 1994-03-23 | — | — | EP | disclosed |
| US-5141952-A | Bactericides | ROUSSEL UCLAF (FR) | 1992-08-25 | — | — | US | disclosed |
| US-5081135-A | Bactericides | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| EP-0418143-A1 | Dicarboxylic acids derivatives containing a nitrogen or oxygen heteroring, process for their preparation and their use as medicines | ROUSSEL-UCLAF (FR) | 1991-03-20 | — | — | EP | disclosed |