Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935611 | 0.92 | CYP3A4 (0.50) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL936317 | 0.89 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1KCNN4 | |
| SCHEMBL246639 | 0.87 | SMN1; SMN2 (0.52) | KMT2AMEN1SMN1; SMN2LMNAKCNN4 | |
| SCHEMBL28539349 | 0.85 | CHRM2 (0.50) | KMT2AMEN1SMN1; SMN2LMNAKCNN4 | |
| SCHEMBL10784555 | 0.84 | ESR1 (0.52) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11623260 | 0.84 | ALDH1A1 (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL11015940 | 0.82 | L3MBTL1 (0.49) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL10598204 | 0.82 | ESR1 (0.57) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11764401 | 0.82 | SMN1; SMN2 (0.44) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5930993 | 0.82 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039589-A | LIVER MICROSOMAL ENZYMES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1977-08-02 | — | — | US | disclosed |