Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 6/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936328 | 1.00 | ALOX5 (0.42) | ALOX5POLBGFERMMP1GPR84 | |
| SCHEMBL936009 | 0.89 | POLB (0.39) | POLBGFERMMP1GPR84MMP2 | |
| SCHEMBL936885 | 0.89 | POLB (0.39) | POLBGFERMMP1GPR84MMP2 | |
| SCHEMBL959641 | 0.88 | POLB (0.39) | POLBGFERGPR84ALDH1A1LMNA | |
| SCHEMBL959640 | 0.88 | POLB (0.39) | POLBGFERGPR84ALDH1A1LMNA | |
| SCHEMBL936803 | 0.87 | POLB (0.41) | POLBGFERGPR84ALDH1A1LMNA | |
| SCHEMBL935885 | 0.87 | MAPT (0.41) | POLBGFERGPR84ALDH1A1LMNA | |
| SCHEMBL957128 | 0.85 | POLB (0.44) | POLBGFERMMP1GPR84ALDH1A1 | |
| SCHEMBL962320 | 0.85 | POLB (0.44) | POLBGFERMMP1GPR84ALDH1A1 | |
| SCHEMBL957127 | 0.85 | POLB (0.44) | POLBGFERMMP1GPR84ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010748-A1 | INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE | 味の素株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |