Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959641 | 1.00 | POLB (0.39) | POLBGFERSTAT3GPR84ECE1 | |
| SCHEMBL936885 | 0.90 | POLB (0.39) | POLBGFERGPR84ECE1 | |
| SCHEMBL936009 | 0.90 | POLB (0.39) | POLBGFERGPR84ECE1 | |
| SCHEMBL936327 | 0.88 | ALOX5 (0.42) | POLBGFERGPR84MAPTALDH1A1 | |
| SCHEMBL936328 | 0.88 | ALOX5 (0.42) | POLBGFERGPR84MAPTALDH1A1 | |
| SCHEMBL935885 | 0.88 | MAPT (0.41) | POLBGFERGPR84ECE1GAA | |
| SCHEMBL936803 | 0.88 | POLB (0.41) | POLBGFERSTAT3GPR84ECE1 | |
| SCHEMBL957128 | 0.86 | POLB (0.44) | POLBGFERSTAT3GPR84MAPT | |
| SCHEMBL962320 | 0.86 | POLB (0.44) | POLBGFERSTAT3GPR84MAPT | |
| SCHEMBL957127 | 0.86 | POLB (0.44) | POLBGFERSTAT3GPR84MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010748-A1 | INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE | 味の素株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |