Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.50 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364551 | 0.92 | MAPK1 (0.49) | DRD3CYP3A4HTTBAZ2BCYP4Z1 | |
| SCHEMBL9363661 | 0.91 | ALDH1A1 (0.58) | DRD3CYP3A4HTTBAZ2BCYP4Z1 | |
| Hydrochloric Acid SCHEMBL9363955 | 0.90 | BLM (0.59) | DRD3CYP3A4HTTBAZ2BCYP4Z1 | |
| SCHEMBL9363630 | 0.88 | DRD3 (0.55) | DRD3CYP3A4HTTBAZ2BCYP4Z1 | |
| Hydrochloric Acid SCHEMBL9364164 | 0.87 | DRD3 (0.54) | DRD3CYP3A4HTTBAZ2BCYP4Z1 | |
| Imidazole SCHEMBL10562843 | 0.87 | POLB (0.47) | DRD3HTTCYP4Z1DRD2ADRB2 | |
| SCHEMBL7068530 | 0.86 | NAAA (0.63) | DRD3CYP3A4HTTBAZ2BCYP4Z1 | |
| SCHEMBL4674989 | 0.85 | CYP3A4 (0.60) | DRD3CYP3A4HTTBAZ2BCYP4Z1 | |
| SCHEMBL10566567 | 0.84 | CYP19A1 (0.49) | DRD3CYP3A4HTTBAZ2BCYP4Z1 | |
| Imidazole SCHEMBL10565485 | 0.81 | POLB (0.46) | DRD3HTTCYP4Z1DRD2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290377-B1 | Substituted 4-[1H-Imidazol-1-yl] benzamides as antiarrhythmic agents | SCHERING AG (DE) | 1994-03-02 | — | — | EP | disclosed |