4-Methylbenzoic Acid

4-Methylbenzoic Acid

SCHEMBL147465

Cc1ccc(C(=O)O)cc1.Cc1ccc(C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
SRD5A2 P31213 3/20 0.85
TSHR P16473 3/20 0.71
TP53 P04637 1/20 0.71
CES2 O00748 2/20 0.65
CES1 P23141 2/20 0.65
LMNA P02545 2/20 0.65
RXRA P19793 1/20 0.60
RXRB P28702 1/20 0.60
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA12 O43570 1/20 0.57
CA3 P07451 1/20 0.57
TYR P14679 1/20 0.57
DRD1 P21728 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methylbenzoic Acid SCHEMBL93638 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL11366477 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
Terephthalic Acid SCHEMBL526449 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
Terephthalic Acid SCHEMBL15994097 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL1331178 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6113245 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6914468 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6112949 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL1042425 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6912547 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116286066-A Bamboo vinegar powder extract and identification method and application of active ingredients thereof 厦门医学院 2023-06-23 CN disclosed
CN-107207395-A The manufacture method of p-methylbenzoic acid 东丽株式会社 2017-09-26 CN disclosed
CN-105517987-B Process for recovering water, metals and organic materials from the production of polycarboxylic acids 约翰逊·马泰·戴维技术有限公司 2017-09-19 CN disclosed
CN-105517987-A Process for recovering water, metals and organic materials from the production of polycarboxylic acids JOHNSON MATTHEY DAVY TECHNOLOGIES LTD 2016-04-20 CN disclosed
CN-103121950-A Method of refining crude terephthalic acid HITACHI PLANT TECHNOLOGIES KK 2013-05-29 CN disclosed
US-20120058024-A1 SYSTEM AND PROCESS FOR PRODUCTION OF BENZOIC ACIDS AND PHTHALIC ACIDS H R D CORPORATION (US) 2012-03-08 US disclosed
US-7994330-B2 Oxidizing p-xylene to terephthalic acid using a catalyst having a dicarboximide skeleton; hydrothermally treating the product with hot water, decomposing and removing catalyst impurities DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2011-08-09 US disclosed
WO-2011031424-A2 HIGH SHEAR SYSTEM AND METHOD FOR THE PRODUCTION OF ACIDS HRD CORPORATION (US) 2011-03-17 WO disclosed
US-20110031000-A1 RESIN COMPOSITION, CARRIER MATERIAL WITH RESIN, MULTI-LAYERED PRINTED CIRCUIT BOARD, AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2011-02-10 US disclosed
US-20090092975-A1 SELECTABLE MARKER MOLOGIC LTD (GB) 2009-04-09 US disclosed
US-4500732-A SOLVENT EXTRACTION USING P-XYLENE STANDARD OIL COMPANY (INDIANA) (US) 1985-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090092975-A1 SELECTABLE MARKER AMD1, PADI1, PSAT1 ALDH1A1 46/4885SMN1; SMN2 3648/4885SRD5A2 1190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.