SCHEMBL9364002

SCHEMBL9364002

CC(=O)c1ccccc1C(=O)c1cccs1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.71
LMNA P02545 2/20 0.71
HPGDS O60760 1/20 0.56
MAPT P10636 5/20 0.51
ALDH1A1 P00352 3/20 0.51
PSMD14 O00487 1/20 0.51
MMP2 P08253 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
THRB P10828 1/20 0.49
NPC1 O15118 6/20 0.49
RAB9A P51151 6/20 0.49
CTNNB1 P35222 1/20 0.49
WNT3A P56704 1/20 0.49
DAO P14920 1/20 0.48
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
MEN1 O00255 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9148337 0.90 LMNA (0.85) ALOX15LMNAHPGDSMAPTALDH1A1
SCHEMBL11704482 0.84 ALOX15 (0.56) ALOX15LMNAHPGDSMAPTALDH1A1
SCHEMBL3859942 0.83 ALOX15 (1.00) ALOX15LMNAHPGDSMAPTALDH1A1
SCHEMBL10174797 0.81 CTNNB1 (0.66) ALOX15LMNAHPGDSMAPTALDH1A1
SCHEMBL13721557 0.81 ALOX15 (0.65) ALOX15LMNAHPGDSMAPTALDH1A1
SCHEMBL11930062 0.80 ALOX15 (0.64) ALOX15LMNAHPGDSMAPTALDH1A1
SCHEMBL10618289 0.79 ALOX15 (0.68) ALOX15LMNAHPGDSMAPTALDH1A1
SCHEMBL11490952 0.79 ALOX15 (0.62) ALOX15LMNAHPGDSMAPTALDH1A1
SCHEMBL10136508 0.79 LMNA (0.62) ALOX15LMNAHPGDSMAPTALDH1A1
SCHEMBL8987356 0.78 TSHR (0.57) ALOX15LMNAHPGDSMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4268539-A INDIUM NITRATE-DIKETONE REACTION PRODUCT TOKYO DENSHI KAGAKU KABUSHIKI KAISHA (JP) 1981-05-19 US claimed
EP-0372922-B1 Preparation process of N-substituted maleimides MITSUI TOATSU CHEMICALS (JP) 1994-03-09 EP disclosed
US-5175309-A Forming an imide by heat catalytic dehydration MITSUI TOATSU CHEMICALS INC. (JP) 1992-12-29 US disclosed
EP-0372922-A2 Preparation process of N-substituted maleimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-06-13 EP disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed
US-4268539-A INDIUM NITRATE-DIKETONE REACTION PRODUCT TOKYO DENSHI KAGAKU KABUSHIKI KAISHA (JP) 1981-05-19 US disclosed