Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | HPGDS | O60760 | 1/20 | 0.63 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148337 | 0.92 | LMNA (0.85) | ALOX15LMNAKMT2AMEN1HPGDS | |
| SCHEMBL9364002 | 0.83 | ALOX15 (0.71) | ALOX15LMNAKMT2AMEN1HPGDS | |
| SCHEMBL11029526 | 0.82 | ALOX15 (0.70) | ALOX15LMNAKMT2AMEN1HPGDS | |
| SCHEMBL6001619 | 0.81 | ALOX15 (0.68) | ALOX15LMNAKMT2AMEN1HPGDS | |
| SCHEMBL10618289 | 0.81 | ALOX15 (0.68) | ALOX15LMNAKMT2AMEN1HPGDS | |
| SCHEMBL27814080 | 0.80 | ALOX15 (0.67) | ALOX15LMNAKMT2AMEN1HPGDS | |
| SCHEMBL1424601 | 0.79 | ALOX15 (0.66) | ALOX15LMNAKMT2AMEN1HPGDS | |
| SCHEMBL10174797 | 0.79 | CTNNB1 (0.66) | ALOX15LMNAKMT2AMEN1HPGDS | |
| SCHEMBL9821675 | 0.79 | TP53 (0.66) | ALOX15LMNAKMT2AMEN1HPGDS | |
| SCHEMBL11434037 | 0.79 | LMNA (0.66) | ALOX15LMNAKMT2AMEN1HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108751210-A | A kind of method for calcinating of glass sand | 新疆能源（集团）晶拓科技材料有限责任公司 | 2018-11-06 | — | — | CN | claimed |
| US-10711027-B2 | DNA polymerase beta inhibitors | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-07-14 | — | — | US | disclosed |
| EP-2259377-B1 | SOLAR CELL | SHARP KK (JP) | 2020-06-03 | — | — | EP | disclosed |
| US-20190202853-A1 | DNA POLYMERASE BETA INHIBITORS | THE JOHNS HOPKINS UNIVERSITY | 2019-07-04 | — | — | US | disclosed |
| EP-2828904-B1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | RAYNERGY TEK INC (TW) | 2019-06-12 | — | — | EP | disclosed |
| CN-108751210-A | A kind of method for calcinating of glass sand | 新疆能源（集团）晶拓科技材料有限责任公司 | 2018-11-06 | — | — | CN | disclosed |
| EP-2828903-B1 | OPTOELECTRONIC DEVICES COMPRISING POLYMERIC BLENDS | RAYNERGY TEK INC (TW) | 2017-11-01 | — | — | EP | disclosed |
| US-9312501-B2 | Semiconducting compounds and optoelectronic devices incorporating same | POLYERA CORPORATION (US) | 2016-04-12 | — | — | US | disclosed |
| US-9312501-B2 | Semiconducting compounds and optoelectronic devices incorporating same | POLYERA CORPORATION (US) | 2016-04-12 | — | — | US | disclosed |
| US-9312501-B2 | Semiconducting compounds and optoelectronic devices incorporating same | POLYERA CORPORATION (US) | 2016-04-12 | — | — | US | disclosed |
| US-5624922-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1997-04-29 | — | — | US | disclosed |
| US-5585385-A | USEFUL IN TREATING DISORDERS OF MICTURITION; ADMINISTERING TO INHIBIT PLASMA EXTRAVASATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0597540-B1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC (US) | 1996-06-05 | — | — | EP | disclosed |
| CN-1107476-A | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-30 | — | — | CN | disclosed |
| EP-0652218-A1 | Heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5380721-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0597540-A1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1994-05-18 | — | — | EP | disclosed |
| EP-0475527-A2 | Aryl-fused and hetaryl-fused-2, 4-diazepine and 2, 4-diazocine antiarrhythmic agents | STERLING DRUG INC. (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4505921-A | Sulfonylurea compounds and their use in treating diabetes | ADIR, S.A.R.L. (FR) | 1985-03-19 | — | — | US | disclosed |
| US-3994920-A | APPETITE SUPPRESSANT, ANTIDEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10711027-B2 | DNA polymerase beta inhibitors | POLB, POLH, POLN | ALOX15 3938/4885LMNA 1083/4885KMT2A 2832/4885 |
| US-20190202853-A1 | DNA POLYMERASE BETA INHIBITORS | POLB, POLH, POLN | ALOX15 3938/4885LMNA 1083/4885KMT2A 2832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.