Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773406 | 0.95 | CA12 (0.43) | HTTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL11022255 | 0.85 | MEN1 (0.44) | LMNA | |
| SCHEMBL6605344 | 0.85 | TDP1 (0.42) | HTTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL6605334 | 0.82 | CA12 (0.43) | HTTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL9773547 | 0.82 | CA12 (0.57) | HTTCA12CA1CA2CA7 | |
| SCHEMBL9010034 | 0.78 | PTGS2 (0.38) | LMNATDP1 | |
| SCHEMBL9428238 | 0.78 | FFAR4 (0.46) | HTTSMN1; SMN2LTA4HPPARGPPARA | |
| SCHEMBL1109910 | 0.77 | ALDH1A1 (0.40) | HTTSMN1; SMN2LMNA | |
| SCHEMBL872698 | 0.77 | ALDH1A1 (0.38) | HTTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL1619491 | 0.77 | MAPT (0.47) | CACNA1BPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388665-B1 | Substituted N-hydroxypyrazoles and N-hydroxy-triazoles and their use in combatting parasites | BASF AG (DE) | 1994-04-27 | — | — | EP | disclosed |
| US-5280036-A | Containing 4h-1,24-triazole ring | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5214064-A | Insecticides, nematocides, miticides | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| US-5187182-A | Insecticides, nematocides | BASF AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5185359-A | N-phenoxphenyloxymethyl substituted azoles and method for controlling pests therewith | BASF AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | disclosed |
| US-5173501-A | Nematocides, insecticides | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| US-5116860-A | N-SUBSTITUTED AZOLES FOR COMBATING INSECTS, ARACHNIDS AND NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| EP-0388665-A1 | Substituted N-hydroxypyrazoles and N-hydroxy-triazoles and their use in combatting parasites | BASF Aktiengesellschaft (DE) | 1990-09-26 | — | — | EP | disclosed |
| US-4943585-A | N-substituted azoles and insecticide, arachnicide, and nematocide compositions thereof | BASF AKTIENGESELLSCHAFT (DE) | 1990-07-24 | — | — | US | disclosed |