SCHEMBL11022255

SCHEMBL11022255

Cc1ccc(S(=O)(=O)O)cc1CCOc1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
RAB9A P51151 1/20 0.43
ATM Q13315 1/20 0.43
MAPT P10636 2/20 0.42
TP53 P04637 1/20 0.42
APOBEC3A P31941 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HPGD P15428 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GPR84 Q9NQS5 1/20 0.39
BCL2 P10415 1/20 0.39
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.38
NPY1R P25929 1/20 0.38
NPY2R P49146 1/20 0.38
NPC1 O15118 1/20 0.38
PTGS2 P35354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9773406 0.86 CA12 (0.43) MEN1KMT2ARAB9ANPSR1LMNA
SCHEMBL9364127 0.85 HTT (0.43) LMNA
SCHEMBL9010034 0.80 PTGS2 (0.38) MAPTLMNAALDH1A1PTGS2
SCHEMBL872698 0.79 ALDH1A1 (0.38) MEN1KMT2ARAB9AMAPTHPGD
SCHEMBL1619491 0.79 MAPT (0.47) MAPTALDH1A1
SCHEMBL10596213 0.78 ALDH1A1 (0.41) MAPTHPGDLMNAALDH1A1
SCHEMBL6605344 0.76 TDP1 (0.42) MEN1KMT2ARAB9ANPSR1LMNA
SCHEMBL900004 0.76 GAA (0.38) MEN1KMT2AL3MBTL1HPGDLMNA
SCHEMBL6259776 0.76 S1PR3 (0.36) KMT2AMAPTHPGDLMNAALDH1A1
SCHEMBL1607370 0.76 S1PR3 (0.43) RAB9AMAPTL3MBTL1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0160931-A2 Azolylvinyl ethers BAYER AG (DE) 1985-11-13 EP disclosed