Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377356 | 0.78 | CES2 (0.50) | CES2CES1CA1CA2RAB9A | |
| SCHEMBL15846816 | 0.78 | LMNA (0.52) | RAB9ANPC1MAPTLMNAKMT2A | |
| SCHEMBL229639 | 0.77 | LMNA (0.58) | CES2CES1MAPTSMN1; SMN2LMNA | |
| SCHEMBL3790497 | 0.77 | CES2 (0.59) | CES2CES1CA1CA2PTPRF | |
| SCHEMBL246937 | 0.77 | CES2 (0.59) | CES2CES1CA1CA2PTPRF | |
| SCHEMBL4625785 | 0.75 | CA1 (0.64) | CES2CES1CA1CA2RAB9A | |
| SCHEMBL22775249 | 0.75 | CES2 (0.56) | CES2CES1CA1CA2PTPRF | |
| SCHEMBL27861351 | 0.75 | CES2 (0.56) | CES2CES1CA1CA2PTPRF | |
| SCHEMBL3961850 | 0.74 | HSD17B10 (0.55) | RAB9ANPC1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL28541908 | 0.74 | CYP2C9 (0.46) | CA1CA2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111065623-A | Linker for antibody drug conjugates | 德克萨斯州大学系统董事会 | 2020-04-24 | — | — | CN | disclosed |
| EP-0469045-B1 | SYNTHETIC $i(PSEUDOMONAS) $i(AERUGINOSA) PILIN PEPTIDE AND RELATED VACCINES AND DIAGNOSTICS | UNIV ALBERTA (CA) | 1994-06-15 | — | — | EP | disclosed |
| EP-0119705-B1 | OCTAPEPTIDE VASOPRESSIN ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-09-06 | — | — | EP | disclosed |