SCHEMBL229639

SCHEMBL229639

O=[C]OC(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
F2 P00734 1/20 0.58
TSHR P16473 5/20 0.54
TDP1 Q9NUW8 3/20 0.48
TP53 P04637 1/20 0.48
ALDH1A1 P00352 4/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 2/20 0.47
MAPK1 P28482 1/20 0.47
HIF1A Q16665 1/20 0.47
POLB P06746 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
CES1 P23141 3/20 0.46
CES2 O00748 2/20 0.46
DAO P14920 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PLA2G7 Q13093 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3870676 0.79 LMNA (0.56) LMNAF2TSHRTDP1TP53
SCHEMBL1712916 0.79 LMNA (0.56) LMNAF2TSHRTDP1TP53
SCHEMBL10754186 0.77 LMNA (0.67) LMNAF2TSHRTDP1TP53
Hydrogen Peroxide SCHEMBL28155101 0.77 LMNA (0.67) LMNAF2TSHRTDP1TP53
SCHEMBL9364280 0.77 CES2 (0.50) LMNAKMT2AMAPTMAPK1POLB
SCHEMBL15528861 0.77 LMNA (0.54) LMNAF2TSHRTDP1TP53
SCHEMBL29267952 0.77 LMNA (0.54) LMNAF2TSHRTDP1TP53
SCHEMBL1713098 0.77 TSHR (0.56) LMNAF2TSHRTDP1TP53
SCHEMBL15846816 0.77 LMNA (0.52) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL5592713 0.77 CES2 (0.54) LMNAF2TSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11378884-B2 Extreme ultraviolet photoresist and method TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2022-07-05 US claimed
US-20220175872-A1 THERMOGENIC COMPOSITIONS AND METHODS OHIO STATE INNOVATION FOUNDATION 2022-06-09 US claimed
US-20220162698-A1 PHOTOACTIVE COMPOUNDS AND METHODS FOR BIOMOLECULE DETECTION AND SEQUENCING VIBRANT HOLDINGS, LLC 2022-05-26 US claimed
US-11168365-B2 Photoactive compounds and methods for biomolecule detection and sequencing VIBRANT HOLDINGS, LLC (US) 2021-11-09 US claimed
CN-109553711-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553703-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553706-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-13 CN claimed
US-20200133124-A1 Extreme Ultraviolet Photoresist and Method TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2020-04-30 US claimed
EP-3347362-B1 PROCESS FOR PREPARING CEFTOLOZANE FROM 7-AMINOCEPHALOSPORANIC ACID (7-ACA) SANDOZ AG (CH) 2019-10-23 EP claimed
US-20180348639-A1 Extreme Ultraviolet Photoresist and Method TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2018-12-06 US claimed
US-4534898-A 1-Oxa-1-dethia-cephalosporin derivatives MERCK & CO., INC. (US) 1985-08-13 US claimed
EP-0147181-A2 Thiazolylacetic acid derivatives and their preparation Tanabe Seiyaku Co., Ltd. (JP) 1985-07-03 EP claimed
EP-0050856-B1 NEW PEPTIDE, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING IT FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-12-27 EP claimed
EP-0092830-A2 Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application CIBA-GEIGY AG (CH) 1983-11-02 EP claimed
US-4361511-A ANTIALDOSTERONES HOFFMANN-LA ROCHE INC. (US) 1982-11-30 US claimed
US-4212974-A POLYMER STABILIZERS SANKYO COMPANY LIMITED (JP) 1980-07-15 US claimed
US-4125533-A STABILIZERS SANKYO CO. LTD. (JP) 1978-11-14 US claimed
US-RE29732-E Tripeptide ABBOTT LABORATORIES (US) 1978-08-15 US claimed
US-4044002-A ACYL BROMIDES AND A BROMINE SCAVENGER ELI LILLY AND COMPANY (US) 1977-08-23 US claimed
US-4017488-A Process for preparing 7β-acylamino-7α-alkoxycephalosporins SANKYO COMPANY LIMITED (JA) 1977-04-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220175872-A1 THERMOGENIC COMPOSITIONS AND METHODS LRBA, IAPP, FABP4 LMNA 1305/4885F2 4426/4885TSHR 2369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.