Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | PI4KA | P42356 | 4/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.40 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9648060 | 1.00 | RAB9A (0.47) | RAB9ANPC1SCN4ASMN1; SMN2CYP3A4 | |
| SCHEMBL9650878 | 0.91 | RAB9A (0.46) | RAB9ANPC1SCN4ASMN1; SMN2CYP3A4 | |
| SCHEMBL27692947 | 0.91 | RAB9A (0.46) | RAB9ANPC1SCN4ASMN1; SMN2CYP3A4 | |
| SCHEMBL9364323 | 0.91 | RAB9A (0.46) | RAB9ANPC1SCN4ASMN1; SMN2CYP3A4 | |
| SCHEMBL8977487 | 0.78 | RAB9A (0.49) | RAB9ANPC1SCN4ASMN1; SMN2CYP3A4 | |
| SCHEMBL9620028 | 0.78 | RAB9A (0.53) | RAB9ANPC1SCN4ASMN1; SMN2CYP3A4 | |
| SCHEMBL9844859 | 0.76 | NPC1 (0.43) | RAB9ANPC1SCN4ASMN1; SMN2CYP3A4 | |
| SCHEMBL9620030 | 0.74 | CYP3A4 (0.51) | RAB9ANPC1SCN4ASMN1; SMN2CYP3A4 | |
| SCHEMBL5995942 | 0.72 | FOLH1 (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2896479 | 0.72 | FOLH1 (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292806-B1 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| US-5171854-A | Antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-15 | — | — | US | disclosed |
| EP-0292806-A2 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |