Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620030 | 0.83 | CYP3A4 (0.51) | NPC1RAB9ASMN1; SMN2SCN4AALDH1A1 | |
| SCHEMBL8977487 | 0.80 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2SCN4AALDH1A1 | |
| SCHEMBL9364334 | 0.76 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2SCN4AALDH1A1 | |
| SCHEMBL9648060 | 0.76 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2SCN4AALDH1A1 | |
| SCHEMBL9600741 | 0.73 | ATM (0.54) | ALDH1A1CYP3A4MAPTCYP2C19 | |
| SCHEMBL9620028 | 0.72 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2SCN4AALDH1A1 | |
| SCHEMBL9619945 | 0.71 | CTSS (0.38) | NPC1RAB9ASMN1; SMN2SCN4AALDH1A1 | |
| SCHEMBL8977488 | 0.70 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2SCN4AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9619911 | 0.69 | RAB9A (0.59) | NPC1RAB9ASMN1; SMN2SCN4AALDH1A1 | |
| SCHEMBL74053 | 0.69 | RAB9A (0.68) | NPC1RAB9ASMN1; SMN2SCN4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405217-A1 | 2-Isocephems and 2-oxa-isocephems, process for their preparation and their application as and in medicines | BAYER AG (DE) | 1991-01-02 | — | — | EP | disclosed |