Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619945 | 0.91 | CTSS (0.38) | RAB9ANPC1SCN4ASMN1; SMN2LIPG | |
| SCHEMBL8977464 | 0.86 | LCK (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9620030 | 0.80 | CYP3A4 (0.51) | RAB9ANPC1SCN4ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9844859 | 0.80 | NPC1 (0.43) | RAB9ANPC1SCN4ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9364669 | 0.80 | IRAK4 (0.43) | RAB9ANPC1LMNAL3MBTL1 | |
| SCHEMBL10627562 | 0.79 | CTSS (0.43) | RAB9ANPC1ALDH1A1MAPTGAA | |
| SCHEMBL9648060 | 0.78 | RAB9A (0.47) | RAB9ANPC1SCN4ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9364334 | 0.78 | RAB9A (0.47) | RAB9ANPC1SCN4ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10926694 | 0.77 | CTSS (0.41) | MAPTGAA | |
| SCHEMBL7130741 | 0.76 | EPHX2 (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195947-B1 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1996-04-24 | — | — | EP | disclosed |
| EP-0292806-B1 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| EP-0292808-B1 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1994-03-02 | — | — | EP | disclosed |
| US-5171854-A | Antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-15 | — | — | US | disclosed |
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4973685-A | PENICILLINS AND CEPHALOSPORINS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-27 | — | — | US | disclosed |
| EP-0310909-A2 | Heteroannelated phenyl glycine beta-lactam antibiotics, process for their preparation and their use as therapeutical agents | BAYER AG (DE) | 1989-04-12 | — | — | EP | disclosed |
| EP-0292806-A2 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |