Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499823 | 0.89 | TSHR (0.47) | MEN1KMT2AALDH1A1MCL1BCL2L1 | |
| SCHEMBL9363849 | 0.89 | MEN1 (0.45) | MEN1KMT2AALDH1A1MCL1BCL2L1 | |
| SCHEMBL9363724 | 0.88 | MEN1 (0.47) | MEN1KMT2AALDH1A1MCL1BCL2L1 | |
| SCHEMBL9363879 | 0.86 | MEN1 (0.46) | MEN1KMT2AALDH1A1MCL1BCL2L1 | |
| SCHEMBL9363458 | 0.84 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1MCL1BCL2L1 | |
| SCHEMBL9500642 | 0.82 | MEN1 (0.44) | MEN1KMT2AALDH1A1MCL1BCL2L1 | |
| SCHEMBL9499692 | 0.82 | TSHR (0.44) | MEN1KMT2AALDH1A1MCL1BCL2L1 | |
| SCHEMBL9367198 | 0.82 | SLC22A12 (0.60) | MEN1KMT2AALDH1A1MCL1SLC22A12 | |
| SCHEMBL9363563 | 0.81 | CA2 (0.50) | MEN1KMT2AALDH1A1MCL1KCNA5 | |
| SCHEMBL9363397 | 0.81 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447013-B1 | Fluorobenzene sulphonamides | SCHERING AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |
| EP-0447013-A1 | Fluorobenzene sulphonamides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |