Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499823 | 0.91 | TSHR (0.47) | TSHRKCNA5MRGPRX1ALDH1A1MEN1 | |
| SCHEMBL9363849 | 0.89 | MEN1 (0.45) | KCNA5MRGPRX1ALDH1A1MEN1KMT2A | |
| SCHEMBL9499366 | 0.84 | SLC22A12 (0.53) | TSHRMEN1KMT2AHIF1ASLC22A12 | |
| SCHEMBL9500642 | 0.83 | MEN1 (0.44) | TSHRKCNA5MRGPRX1ALDH1A1MEN1 | |
| SCHEMBL9364368 | 0.82 | MEN1 (0.47) | TSHRKCNA5MRGPRX1ALDH1A1MEN1 | |
| SCHEMBL9364281 | 0.81 | MEN1 (0.43) | TSHRKCNA5MRGPRX1ALDH1A1MEN1 | |
| SCHEMBL9363428 | 0.81 | TSHR (0.45) | TSHRMRGPRX1ALDH1A1MEN1KMT2A | |
| SCHEMBL9501405 | 0.81 | KMT2A (0.41) | MRGPRX1ALDH1A1KMT2AEPHX2PPARG | |
| SCHEMBL9363724 | 0.80 | MEN1 (0.47) | KCNA5MRGPRX1ALDH1A1MEN1KMT2A | |
| SCHEMBL9501345 | 0.79 | EPHX2 (0.37) | MRGPRX1ALDH1A1KMT2AKDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |