Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364404 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9364429 | 0.87 | DHODH (0.45) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9364432 | 0.87 | DHODH (0.45) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11274535 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3482698 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6394012 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13761867 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4911666 | 0.85 | MAPT (0.53) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4911670 | 0.85 | MAPT (0.53) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7992908 | 0.85 | MAPT (0.53) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |