SCHEMBL4911666

SCHEMBL4911666

CCOC(=O)/C=C(/C(=O)OCC)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.53
ALDH1A1 P00352 5/20 0.53
KMT2A Q03164 5/20 0.51
MEN1 O00255 4/20 0.51
NPSR1 Q6W5P4 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.47
TDP1 Q9NUW8 2/20 0.46
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
NPC1 O15118 1/20 0.45
GAA P10253 1/20 0.44
KDM4E B2RXH2 3/20 0.44
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.43
GALK1 P51570 1/20 0.43
CCR6 P51684 1/20 0.43
BLM P54132 1/20 0.43
MCL1 Q07820 1/20 0.43
HKDC1 Q2TB90 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992908 1.00 MAPT (0.53) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL4911670 1.00 MAPT (0.53) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL9726821 0.90 MAPT (0.47) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL30769601 0.88 ALDH1A1 (0.47) MAPTALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL11274535 0.88 ALDH1A1 (0.54) MAPTALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL6394012 0.88 ALDH1A1 (0.54) MAPTALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL3482698 0.88 ALDH1A1 (0.54) MAPTALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL5694726 0.87 NPSR1 (0.50) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL13761867 0.87 ALDH1A1 (0.53) MAPTALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL5694725 0.87 NPSR1 (0.50) MAPTALDH1A1KMT2AMEN1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1791901-B1 STABILIZATION OF ORGANIC MATERIALS BASF SE (DE) 2018-03-28 EP disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 US disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 US disclosed
EP-1791901-A2 STABILIZATION OF ORGANIC MATERIALS Ciba SC Holding AG (CH) 2007-06-06 EP disclosed
WO-2006024611-A2 STABILIZATION OF ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269382-A1 Stabilization of Organic Materials LPO, PPOX, HMOX1 MAPT 128/4885ALDH1A1 129/4885KMT2A 1853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.