Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223979 | 0.71 | MEN1 (0.37) | FAAHMEN1KMT2ASMN1; SMN2CYP2C9 | |
| SCHEMBL5256444 | 0.70 | SLC1A3 (0.61) | FAAHMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL8607221 | 0.70 | SLC1A3 (0.61) | FAAHMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL5256446 | 0.70 | SLC1A3 (0.61) | FAAHMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL9411069 | 0.70 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2CCR1CYP2C9 | |
| SCHEMBL9185963 | 0.69 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL4594817 | 0.69 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28968068 | 0.68 | L3MBTL1 (0.49) | MEN1KMT2A | |
| SCHEMBL28232199 | 0.68 | CYP1A2 (0.54) | FAAHCYP2C9CYP2C19CYP1A2HTT | |
| SCHEMBL8086793 | 0.68 | KMT2A (0.52) | MEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425925-B1 | Substituted amino acid amide derivatives, their preparation and use | BAYER AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| EP-0425925-A2 | Substituted amino acid amide derivatives, their preparation and use | BAYER AG (DE) | 1991-05-08 | — | — | EP | disclosed |