Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075350 | 1.00 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2CTSKCTSS | |
| SCHEMBL7304711 | 0.87 | CTSK (0.44) | KMT2AMEN1SMN1; SMN2CTSKCTSS | |
| SCHEMBL7307182 | 0.87 | CTSK (0.44) | KMT2AMEN1SMN1; SMN2CTSKCTSS | |
| SCHEMBL8612019 | 0.83 | ANPEP (0.47) | KMT2AMEN1SMN1; SMN2CTSKCTSS | |
| SCHEMBL8612961 | 0.82 | CTSL (0.58) | KMT2AMEN1SMN1; SMN2CTSKCTSS | |
| SCHEMBL8083658 | 0.82 | CTSK (0.46) | KMT2AMEN1CTSKCTSSCTSL | |
| SCHEMBL8617454 | 0.81 | CA2 (0.51) | KMT2ACTSKCTSSCA2CTSL | |
| SCHEMBL7306604 | 0.79 | MAPT (0.46) | KMT2AMEN1CTSKCTSSCTSL | |
| SCHEMBL7373764 | 0.78 | CTSK (0.58) | KMT2AMEN1SMN1; SMN2CTSKCTSS | |
| SCHEMBL7353047 | 0.77 | CTSK (0.45) | KMT2AMEN1CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |