Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10335474 | 0.84 | ALDH1A1 (0.56) | POLBPPARAALDH1A1CYP1A2CYP2E1 | |
| SCHEMBL21102450 | 0.81 | ALDH1A1 (0.57) | PPARAPTGS2ALDH1A1CYP1A2CYP2E1 | |
| SCHEMBL4277119 | 0.81 | ALDH1A1 (0.57) | PPARAPTGS2ALDH1A1CYP1A2CYP2E1 | |
| SCHEMBL4411960 | 0.81 | ALDH1A1 (0.57) | PPARAPTGS2ALDH1A1CYP1A2CYP2E1 | |
| SCHEMBL7371689 | 0.81 | ALDH1A1 (0.60) | PTGS2ALDH1A1CYP1A2CNR2HDAC3 | |
| SCHEMBL4406395 | 0.80 | ALDH1A1 (0.58) | PPARAPTGS2ALDH1A1CYP1A2CYP2E1 | |
| SCHEMBL9364409 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAAFFAR1PPARD | |
| SCHEMBL4271362 | 0.80 | MTNR1A (0.58) | PTGS2ALDH1A1CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL4272836 | 0.80 | MTNR1A (0.58) | PTGS2ALDH1A1CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL4267817 | 0.80 | MTNR1A (0.58) | PTGS2ALDH1A1CYP1A2CYP2E1CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990650-A | Lipoxygenase, cyclooxygenase inhibitors | TEIJIN LIMITED (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0273678-A2 | Aromatic derivative and preparation method thereof | TEIJIN LIMITED (JP) | 1988-07-06 | — | — | EP | disclosed |