Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427372 | 0.90 | KDM4E (0.58) | MAOBMAOABCHEACHEKDM4E | |
| SCHEMBL3445791 | 0.86 | MAOB (0.54) | MAOBMAOABCHEACHEKDM4E | |
| SCHEMBL3444912 | 0.86 | MAOB (0.54) | MAOBMAOABCHEACHEKDM4E | |
| SCHEMBL8374655 | 0.85 | MAOA (0.62) | MAOBMAOATSHR | |
| SCHEMBL8716037 | 0.85 | MAOA (0.62) | MAOBMAOATSHR | |
| SCHEMBL8374654 | 0.85 | MAOA (0.62) | MAOBMAOATSHR | |
| SCHEMBL3445348 | 0.84 | KDM4E (0.52) | MAOBMAOABCHEACHEKDM4E | |
| SCHEMBL8863665 | 0.84 | TSHR (0.59) | MAOBMAOATSHR | |
| SCHEMBL10497495 | 0.84 | TSHR (0.59) | MAOBMAOATSHR | |
| SCHEMBL584671 | 0.84 | TSHR (0.59) | MAOBMAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410359-B1 | Substituted aminoalkoxy-benzene-derivatives | HOFFMANN LA ROCHE (CH) | 1994-01-26 | — | — | EP | disclosed |
| US-5214046-A | Synergistic mixtures, inhibitors of sterol biosynthesis | HOFFMANN-LA ROCHE INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5106878-A | Synergistic effects with other fungicides | HOFFMANN-LA ROCHE INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0410359-A1 | Substituted aminoalkoxy-benzene-derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | disclosed |