Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636993 | 0.84 | HTR2A (0.50) | SLC6A4SLC6A2SLC6A3HPGDMEN1 | |
| SCHEMBL31596156 | 0.84 | HTR2A (0.50) | SLC6A4SLC6A2SLC6A3HPGDMEN1 | |
| SCHEMBL10564000 | 0.81 | ALDH1A1 (0.46) | SLC6A4SLC6A2SLC6A3HPGDCYP3A4 | |
| SCHEMBL4863460 | 0.81 | ALDH1A1 (0.41) | SLC6A4SLC6A2SLC6A3HPGDMEN1 | |
| SCHEMBL10569734 | 0.81 | ALDH1A1 (0.40) | SLC6A4SLC6A2SLC6A3HPGDKMT2A | |
| SCHEMBL10566854 | 0.81 | KEAP1 (0.58) | SLC6A4SLC6A2SLC6A3HPGDMEN1 | |
| SCHEMBL5703567 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8763318 | 0.80 | ALDH1A1 (0.50) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8993309 | 0.78 | MAPT (0.41) | SLC6A4HPGDMEN1KMT2AMAPT | |
| SCHEMBL28159688 | 0.78 | SNCA (0.46) | SLC6A4SLC6A2SLC6A3HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445698-B1 | Thiocarbamoylacetonitrile compounds | MITSUBISHI CHEM IND (JP) | 1994-06-22 | — | — | EP | disclosed |
| US-5246958-A | Thiocarbamoylacetonitriles | MITSUBISHI KASEI CORPORATION (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0445698-A1 | Thiocarbamoylacetonitrile compounds | MITSUBISHI KASEI CORPORATION (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4874763-A | ANTIARRHYTHMIA AGENTS | ROEHM GMBH CHEMISCHE FABRIK (DE) | 1989-10-17 | — | — | US | disclosed |
| EP-0318795-A2 | Pharmaceutically active pteridin derivatives | Röhm GmbH (DE) | 1989-06-07 | — | — | EP | disclosed |