Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360730 | 0.87 | L3MBTL1 (0.70) | LMNAKMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8485405 | 0.82 | LMNA (1.00) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4911962 | 0.81 | KMT2A (0.71) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9360670 | 0.81 | TP53 (0.54) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4910018 | 0.79 | KMT2A (0.81) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4736437 | 0.79 | KMT2A (0.81) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9473982 | 0.79 | KMT2A (0.75) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9360242 | 0.77 | MAPT (0.45) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8689047 | 0.76 | LMNA (0.75) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL14066070 | 0.76 | KMT2A (0.75) | LMNAKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |