Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.54 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364442 | 0.87 | LMNA (0.69) | L3MBTL1KDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL4732827 | 0.82 | L3MBTL1 (1.00) | L3MBTL1KDM4EALDH1A1MAPK10LMNA | |
| SCHEMBL4732905 | 0.81 | L3MBTL1 (0.81) | L3MBTL1KDM4EALDH1A1MAPK10LMNA | |
| SCHEMBL8689099 | 0.78 | L3MBTL1 (0.75) | L3MBTL1KDM4EALDH1A1MAPK10LMNA | |
| SCHEMBL9360670 | 0.78 | TP53 (0.54) | L3MBTL1KDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL10502377 | 0.73 | KMT2A (1.00) | L3MBTL1KDM4EALDH1A1MAPK10MAPK1 | |
| SCHEMBL7463414 | 0.73 | L3MBTL1 (0.60) | L3MBTL1KDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL4734002 | 0.72 | LMNA (1.00) | L3MBTL1KDM4EALDH1A1MAPK10LMNA | |
| SCHEMBL12127483 | 0.72 | MAPT (0.72) | L3MBTL1KDM4EALDH1A1MAPK10LMNA | |
| SCHEMBL9360242 | 0.72 | MAPT (0.45) | L3MBTL1KDM4EALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |