SCHEMBL9364780

SCHEMBL9364780

COCCOCOc1ccc([C@@H](O)C(=O)OC(c2ccccc2)c2ccccc2)cc1OCOCCOC

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.39
RARG P13631 9/20 0.37
RARA P10276 1/20 0.37
RARB P10826 1/20 0.37
F2 P00734 1/20 0.36
ELANE P08246 1/20 0.36
HTR1A P08908 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
KIF11 P52732 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
BLM P54132 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9364775 1.00 FDPS (0.39) FDPSRARGRARARARBF2
SCHEMBL8435541 0.89 RARG (0.37) FDPSRARGRARARARBF2
SCHEMBL9362238 0.88 RARG (0.38) FDPSRARGRARARARBF2
SCHEMBL9361830 0.86 RARG (0.36) FDPSRARGRARARARBF2
SCHEMBL8380382 0.84 RARG (0.36) RARGRARARARBF2ELANE
SCHEMBL9364664 0.80 PDE4B (0.45)
SCHEMBL5090772 0.76 FDPS (0.48) FDPSNPSR1BLM
SCHEMBL8550659 0.76 RARG (0.33) RARGKIF11
SCHEMBL8379337 0.75 KMT2A (0.32) RARGHTR1AADRA1DADRA1AADRA1B
SCHEMBL5092331 0.74 BLM (0.51) FDPSNPSR1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241901-B1 Cephalosporin derivatives, processes for their preparation and antibacterial agents BANYU PHARMA CO LTD (JP) 1994-08-24 EP disclosed
EP-0238061-B1 CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS Banyu Pharmaceutical Co., Ltd. (JP) 1992-10-21 EP disclosed
US-5061794-A Effective against pseudomonads BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-10-29 US disclosed
US-4988687-A Thiazoleoxyimineacetamido carboxymethylpyridinium derivatives of cephalosporins BANYU PHARMACEUTICAL COMPANY, LTD. (JP) 1991-01-29 US disclosed
US-4880797-A THIAZOLE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-11-14 US disclosed
EP-0241901-A2 Cephalosporin derivatives, processes for their preparation and antibacterial agents Banyu Pharmaceutical Co., Ltd. (JP) 1987-10-21 EP disclosed
EP-0238061-A2 Cephalosporin derivatives, processes for their preparation and antibacterial agents Banyu Pharmaceutical Co., Ltd. (JP) 1987-09-23 EP disclosed