Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390592 | 0.85 | GPR35 (0.68) | GPR35ALDH1A1L3MBTL1GAASETD7 | |
| SCHEMBL11402843 | 0.85 | MAPT (0.63) | GPR35ALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL7025774 | 0.83 | LMNA (0.50) | ALDH1A1L3MBTL1SETD7PDCD1CD274 | |
| SCHEMBL9365252 | 0.82 | MAPT (0.65) | GPR35ALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL9364688 | 0.81 | KMT2A (0.57) | ALDH1A1L3MBTL1GAAMAPTMEN1 | |
| SCHEMBL7025772 | 0.81 | DHODH (0.67) | L3MBTL1GAAPDCD1CD274MAPT | |
| SCHEMBL11453702 | 0.81 | MAPT (0.58) | GPR35ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL11813065 | 0.80 | SETD7 (0.52) | ALDH1A1L3MBTL1SETD7PDCD1CD274 | |
| SCHEMBL7836490 | 0.80 | SETD7 (0.52) | ALDH1A1L3MBTL1SETD7PDCD1CD274 | |
| SCHEMBL23727313 | 0.79 | MAPT (0.57) | ALDH1A1SETD7MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | disclosed |
| US-5061706-A | 2,3-QUINOXALINEDIONES FOR USE AS NEUROLEPTICS | NOVO NORDISK A/S (DK) | 1991-10-29 | — | — | US | disclosed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |