Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934088 | 0.84 | LMNA (0.67) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL11607825 | 0.84 | GPR35 (0.59) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL9364693 | 0.81 | GPR35 (0.58) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL9364633 | 0.81 | SAE1 (0.54) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL11607569 | 0.81 | PTPN11 (0.71) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL6667746 | 0.80 | TDP1 (0.62) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL30368222 | 0.79 | ALDH1A1 (0.66) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL171190 | 0.79 | ALDH1A1 (0.66) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL13753679 | 0.79 | KMT2A (0.66) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL4599065 | 0.79 | LMNA (0.63) | KMT2AMAPTALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | disclosed |
| US-5061706-A | 2,3-QUINOXALINEDIONES FOR USE AS NEUROLEPTICS | NOVO NORDISK A/S (DK) | 1991-10-29 | — | — | US | disclosed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |