Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379337 | 0.88 | KMT2A (0.32) | RARGRAB9ANPC1KMT2ALMNA | |
| SCHEMBL9252923 | 0.87 | RARG (0.32) | RARGRAB9ANPC1KMT2AMAPK1 | |
| SCHEMBL9065459 | 0.87 | KIF11 (0.33) | RARGRAB9ANPC1MAPK1KIF11 | |
| SCHEMBL8380382 | 0.86 | RARG (0.36) | RARGRAB9ANPC1KMT2AHPGD | |
| SCHEMBL7960031 | 0.83 | RARG (0.33) | RARGFFAR4 | |
| SCHEMBL7959833 | 0.78 | RARG (0.35) | RARGRAB9ANPC1FFAR4MAPK1 | |
| SCHEMBL8379339 | 0.78 | HTR1A (0.36) | KMT2ALMNAFFAR4ALDH1A1 | |
| SCHEMBL8133892 | 0.77 | RAB9A (0.33) | RARGRAB9ANPC1KMT2ALMNA | |
| SCHEMBL9364775 | 0.76 | FDPS (0.39) | RARGKIF11 | |
| SCHEMBL9364780 | 0.76 | FDPS (0.39) | RARGKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883248-A | QUATERNARY AMMONIUM INTERMEDIATES | ROUSSEL UCLAF (FR) | 1999-03-16 | — | — | US | disclosed |
| US-5763617-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5712266-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-01-27 | — | — | US | disclosed |