Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | BID | P55957 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364882 | 0.84 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL9364884 | 0.84 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL9503373 | 0.84 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1FAAHBIDBCL2L1 | |
| SCHEMBL9504617 | 0.81 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1FAAHBIDBCL2L1 | |
| SCHEMBL9502631 | 0.80 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PLA2G4BPTGER1PTGER4 | |
| SCHEMBL9504601 | 0.80 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PLA2G4BPLA2G4AFAAH | |
| SCHEMBL9505459 | 0.79 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1DAGLA | |
| SCHEMBL9427991 | 0.74 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9503595 | 0.73 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1FAAH | |
| SCHEMBL9428622 | 0.73 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1PLA2G4BPTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | claimed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | claimed |
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |